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No USB Mouse input on sierra. Keyboard works fine

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I am having no luck trying to get the USB mouse to work am using 

Cpu - amd fx8320E

Nvidia gtx 660 msi

16gb RAM

Asus M5a78L-M LX V2

I have an SSD and running osx on HDD


I have tried several wires usb mice and nothing


Using boot flags. Kernel.amd -v npci=0x3000

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